Pretreatment Evaluation of Chronic Hepatitis C
نویسندگان
چکیده
منابع مشابه
Pretreatment evaluation of chronic hepatitis C: risks, benefits, and costs.
CONTEXT Chronic hepatitis C (CHC) infection affects nearly 4 million people in the United States. Treatment with interferon alfa-2b has been limited by its cost and low likelihood of long-term response. OBJECTIVE To examine the cost-effectiveness of alternative pretreatment management strategies for patients with CHC. DESIGN Decision and cost-effectiveness analysis using a Markov model to e...
متن کامل[Non-invasive evaluation of liver fibrosis in chronic hepatitis C].
Chronic hepatitis C (CHC) is a major public health concern, with around 180 million individuals affected worldwide. Liver fibrosis and its end-point cirrhosis are the main causes of morbidity and mortality in patients with CHC. Liver biopsy (LB) has traditionally been considered the "gold standard" for pre-treatment evaluation of liver fibrossis in patients with CHC. However, LB is an invasive ...
متن کاملChronic Hepatitis C
The goal of antiviral therapy for patients with chronic hepatitis C virus (HCV) infection is to attain a sustained virologic response (SVR), which is defined as undetectable serum HCV-RNA levels at 6 months after the cessation of treatment. Major improvements in antiviral therapy for chronic hepatitis C have occurred in the past decade. The addition of ribavirin to interferon-alfa therapy and t...
متن کاملHistorical treatment of chronic hepatitis B and chronic hepatitis C.
Interferon is currently considered to be the only accepted effective treatment for chronic viral hepatitis. A history of the treatment of chronic hepatitis B and C before the use of interferon is presented here. Hepatitis B virus does not seem to be directly cytopathic and the disease is known to be modulated largely by the host's immune response. Experience with immunosuppressant and immunosti...
متن کاملTreatment of chronic hepatitis C.
Treatment for chronic hepatitis C has changed over the past years achieving higher response rates. The combination treatment with pegylated interferon-a and ribavirin is tailored based on the on-treatment virological responses. With this response-guided therapy, the overall sustained virological response rate is about 55%. Many new antivirals are currently under investigation and some will be c...
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ژورنال
عنوان ژورنال: JAMA
سال: 1998
ISSN: 0098-7484
DOI: 10.1001/jama.280.24.2088